Matt Forte

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SAN FRANCISCO The hardest part of a blowout loss is sorting out what it says about the defeated, first in the game itself and then about the bigger 16-game picture.

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SAN FRANCISCO The San Francisco defense was barely allowing two touchdowns (14.1 points) per game, No.

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SAN FRANCISCO (AP) As Alex Smith stood on the sideline with a concussion, San Francisco's potential quarterback of the future went to work - and fast.

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The loss to Houston hurts even more now that both Green Bay and Minnesota wont stop winning.

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First, the bad news: Neither Jay Cutler nor Jason Campbell have ever beaten the San Francisco 49ers. They are a combined 0-4 with nearly identical passer ratings in the low 50s for those games.

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