Jesse Crain warmed up but didn't appear in Tuesday's game because he experienced right shoulder tightness.
Manager Robin Ventura told CSN Chicago's Chuck Garfien that Crain didn't start the eighth inning as planned after bullpen coach Bobby Thigpen alerted him the right-hander didn't feel right.
Starting pitcher John Danks returned to the mound to start the eighth inning and was lifted for Nate Jones after he allowed a leadoff single.
Crain has been one of the team's most valuable assets thus far. He's 2-3 with a 0.74 ERA in 38 games this season. The veteran, a free agent after this season, could have even more value to the club as a trade chip; Crain is seen as one of the top relievers available to contenders who might want to acquire him.